Synthesis of cis-Pt (NH3)(benzothiazole)Cl2

Cisplatin is a chemotheraphy treatment used in some types of cancers small cell lung cancer, colon cancer and stomach cancer. The disadvantages of this compound are that it is highly toxic and resistant, so their use in treatment is not always effective. Scientists continue seeking new agents that could weak its mechanism of resistance.

I will be investigating the synthesis of cisplatin using like ligand 1,3 benzothiazole. I am very animated with my participation in this project because it is my first time in such a big assignment and I know that it requires a huge responsibility and I am prepared for that.

My mentor in this research is the professor Mayra Cadiz. She has a PhD in Inorganic Chemistry. I choose this area because anything that involves the camp of medicine especially with the research of drugs that can battle cancer enthusiasm me. My experience in the laboratory has been one of the most fantastic I have ever had. I have read a research item related with our work and how important is to make this the best as possible not only by the money it could cost an mistake its because maybe we could discover something that it could beneficiated millions of citizens . My team is composed of persistent and responsible undergraduate students and a great professor which make me feel that our goals will truly fulfill by the end of the semester and for the next year.

Our purpose by the end of the semester is to synthesize cis-Pt(NH₃)(L)Cl₂ where L=1,3 benzothiazole by using K₂PtCl₄ as the starting reagent and find a way to make the Pt increase its transport to the cell and reduce its elimination.